10% discount with code: FIRSTORDER10

10% discount with code: FIRSTORDER10

Tretinoin Cream

Tretinoin Cream UK is the gold standard in anti-aging skincare.

✔️ Anti-Acne

✔️ Anti Wrinkle

✔️ Collagen production plumps out the skin

✔️ Decreases fine lines & wrinkles, reverses photo sun damage


Tretinoin Retin A cream is a medication used for the treatment of acne. It contains tretinoin in a retinol cream base in its purest form also known as retinoic acid and is a generic name for synthetic vitamin A.

Tretinoin is a derived form of Vitamin A. It is used to treat acne by unclogging blocked pores to prevent the formation and spread of acne, pimples, and blackheads. It increases skin cell turnover and reverses sun-damaged skin and Sun/Age spots  It is also used more predominately in advanced Anti-Aging skincare. It effectively works by rapidly increasing skin cell turnover,  increasing collagen production, and removing dead skin cells leaving brighter, more youthful skin, and minimised unclogged pores.


  • Increasing skin cell turnover, revealing a younger, brighter, and more youthful complexion
  • Reversing photodamaged skin Age and Sun Spots
  • Reversing pigmentation and hyperpigmentation
  • Tightens sagging, aging skin
  • Reverses fine lines & wrinkles
  • Evens out skin tone and smooths
  • Plumps out the skin

Retino A is hailed as the holy grail of skincare and is the only product on the market that is scientifically proven to reverse sun damage.


Apply a pea-sized amount to the corners of your eyes, nose, and mouth after cleansing. Always use Retino A as your last product before bed as this allows the tretinoin to be fully absorbed by your skin without any sunlight affecting your skin. It is important to keep your skin hydrated and use SPF 50 the following morning.

Products recommended using with Retin-A tretinoin are Lipidz deeply hydrating rapid barrier cream and Z Block Zinc Oxide SPF 50 which are also available on this website.

The Manufacturer is Janssen pharmaceutical company of Johnson & Johnson.

We always use the freshest batches with the longest expiry dates for complete customer satisfaction.

Does Tretinoin Cream really work?

The short answer for this question about the effectiveness of tretinoin cream is just a simple yes and we will explain to you why Tretinoin is the most sought-after product in topical acne & anti-ageing treatment.

Tretinoin is the only product on the market which has been scientifically proven by healthcare professionals to work on wrinkles. Tretinoin works by irritating the outer epidermis skin cells which then removes tired old dead dull skin cells and speeds up the process of replacing the old dead skin cells with new brighter younger fresher skin cells.

Tretinoin also is effective in the topical treatment of acne vulgaris as it works by affecting the production of skin oils, by changing the way your skin produces oils by reducing the skin’s oil production Tretinoin clears the pores and makes it very difficult for bacteria to breed and cause acne. Patients may experience flare-ups or worse acne when they first start applying Tretinoin due to the irritation it causes it is known as the dreaded purge.

This may happen before the acne improves. during the purge, it is important to carry on using Tretinoin & keep your skin as hydrated as possible as the purge is purely a process some people may experience when first using Tretinoin once you get through the purge your acne will improve.

After long-term usage, Tretinoin is highly effective at clearing and reducing the formation of acne. Here is a list of some of the wonderful benefits of Tretinoin.

  • Treats Acne scars
  • Brightens skin tone
  • Treats acne topically
  • Reduces fine line
  • Diminishes pore size
  • Reduces stretch marks
  • Reduces wrinkles
  • Treats Age spots
  • Unclogs pores
  • Minimizes crows feet
  • Exfoliates dead skin
  • Accelerates skin cell turnover revealing younger brighter youthful skin.

As you can see Tretinoin has a wide range of effective benefits which are not to be missed after being approved by the FDA in 1971. Tretinoin is becoming increasingly popular and to date is the best product in a tube before you head to the dreaded botox.

What is the difference between Retin A Cream and Tretinoin creams?

The names are confusing but they are actually the same product. Retin-A is actually the brand name for the drug tretinoin and tretinoin is the name of the active ingredient in the product. Many companies manufacture topical tretinoin medications, so tretinoin is sold under many different names.

Benefits of Retin A (tretinoin)

Tretinoin creams were originally developed for the treatment of acne and are only available on prescription. However, the patients using the topical Retin A soon noticed that they had fewer wrinkles and age spots.

The main reasons you might want to use might use Retin A is to target acne and pimples, fade acne scars and also to help soften fine lines, fade dark age spots and discolourations, and leave your skin looking brighter and smoother.


Tretinoin Cream FAQ’s

What is Tretinoin?

Tretinoin, also known as all-trans retinoic acid, is a medication used for the treatment of acne and acute promyelocytic leukaemia. For acne, it is applied to the skin as a cream, gel or ointment.

Is Tretinoin a Retinol?

Retinoids are a group of compounds derived from vitamin A. Tretinoin and retinol both fall under this umbrella. Both tretinoin and retinol are topical skin care products that can treat the same conditions. They both promote rapid exfoliation and stimulation of collagen and elastin, which leads to smoother-looking skin.

What Does Tretinoin Do?

Tretinoin (Altreno, Atralin, Avita, Retin-A) is used to treat acne. Tretinoin is also used to reduce fine wrinkles (Refissa and Renova) and to improve spotty discoloration (Renova) and rough feeling skin (Renova) when used along with other skin care and sunlight avoidance programs.

How long does Tretinoin take to work?

You may notice tretinoin starting to work within 2 to 3 weeks, but it can take 6 weeks or more to experience the full benefit. If you don’t see improvement within 12 weeks, or if you have significant improvement and wonder if you should start using it less frequently, talk to your doctor.

Is Tretinoin available in the UK?

Tretinoin is no longer available through GP prescription.

Does Tretinoin Have Side Effects?

Overall, topical tretinoin is a very safe drug with very few side effects. Most users had little or no side effects, according to studies using tretinoin skin treatments, with the cream and gel versions of tretinoin having a “low frequency of reported adverse events.” The key is to understand how to use tretinoin cream correctly and successfully while minimising these potential adverse effects.

The most frequent tretinoin gel, cream, and solution adverse effects include skin redness, abnormal skin peeling, and increased sensitivity to sunlight.

Many of these adverse effects are particularly frequent during the first two to six weeks of tretinoin treatment, which many users refer to as the “purge” or adjustment period of tretinoin. During this time, your skin is more likely to get irritated and peel as the tretinoin begins to act to prevent acne.

Skin Discoloration

The most prevalent negative effect of topical tretinoin is skin redness. A tiny percentage of tretinoin users suffer some degree of redness after using the cream, gel, or solution to the face, usually within the first few days.

Skin redness can develop from a variety of causes. Overuse of tretinoin, either by applying an excessive amount of the topical tretinoin product to your face or by utilising a gel, cream, or solution with an excessive concentration of tretinoin, is a typical cause of excessively red skin.

Tretinoin can speed up the rate at which your skin sheds, which aids in the disappearance of acne. This can also cause transient redness in those with sensitive skin during the first few days or weeks of using tretinoin as the skin adjusts to the medicine.

Most physicians recommend that you start with a modest, pea-sized quantity of tretinoin for your entire face while learning how to apply it. To limit the risk of redness and other skin irritation, start with a low to moderate dosage of topical tretinoin.

Skin Peeling that isn’t Normal

Another typical negative effect of tretinoin cream is abnormal skin peeling. During the first several weeks of therapy, many users report an increase in skin peeling. The peeling is frequently intense, resulting in a sunburn-like texture and skin dryness (similar to the tretinoin “purge”).

Skin peeling is typically caused by tretinoin raising the rate of exfoliation, leading your body to lose old skin faster than usual. Peeling on your face can range from little flakes of dry, flaky skin to huge portions of exfoliated, peeling skin.

Skin peeling from tretinoin, like skin redness, usually goes away after two to six weeks of using the cream, gel, or solution.

Increased Sunlight Sensitivity

Tretinoin is an exfoliator, which means it hastens the process by which your body replaces old skin cells with new ones. Your skin may be more sensitive to sunlight during and during the first few weeks of tretinoin therapy.

Due to heightened sensitivity, it is highly typical for tretinoin users to acquire sunburn sooner than usual during this period.

If you must go out in the sun during the first two to six weeks of tretinoin use, use an SPF 30+ sunscreen to protect your skin from sunburn. In general, you should try to limit your exposure to direct sunlight during the first few weeks of using tretinoin.

Even when the tretinoin “purge” phase is over and your skin has exfoliated, it is critical to protect your skin from the sun. When using tretinoin, applying sunscreen and avoiding excessive sun exposure will help you avoid sunburn and sun damage.

Most physicians also prescribe using tretinoin at night, usually just before going to bed, to reduce the effects of direct sun exposure on your skin.